Lactic acid is an intermediate in carbohydrate metabolism, which is often derived from skeletal muscle. Blood lactate concentration depends on the rate of production in the tissue and the rate of metabolism in the liver. Lactic acidosis occurs in two situations.
- Type A (Hypoxyl): Occurs as a result of reduced oxidation in tissues, such as Hypovplemia shock and lung damage.
- Type B (metabolic): as a result of disease (diabetes mellitus, liver diseases, neoplasia, etc.), poisoning with drugs or toxins (ethanol, methanol, salicates, etc.) or hereditary metabolic disorders.