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pharmacology
Salbutamol selectively stimulates bronchodilator beta-adrenergic receptors, and promotes the expansion of airways.
Pharmacokinetics:
Absorption: Absorbs easily and gently from the gastrointestinal tract.
Broadcast: Passes through the blood-brain barrier.
Metabolism: metabolized by the liver to inactive metabolites.
Disposal: Immediately excreted in urine and faeces
Indications:
• Bronchial spasm in patients with obstructive airway disease
• Prevention of bronchial spasm due to exercise
prohibited usage:
Sensitization or formulation
Caution:
Cardiovascular diseases include coronary artery disease and hypertension, hyperthyroidism, diabetes mellitus and those who are uncommonly responding to adrenergic drugs.
Drug Interactions:
The use of salbutamol in combination with epinephrine and other sympathetic anesthetic amines can increase the sympathetic effects and toxicity of these drugs. Co-administration with MAO inhibitors and three-ring antidepressants has the potential for serious cardiovascular effects.
Other propranolol and beta-blockers may reduce the effects of salbutamol.
side effects:
Central nerves: CNS agitation, dizziness, headache, agitation, muscle tone increase, increased sensation, insomnia, boredom, migraine, anger, tremor, weakness
Cardiovascular: increased blood pressure, palpitations, tachycardia
Gastrointestinal: anorexia, heartburn, increased appetite, nausea, taste changes, vomiting
Metabolic: Hypokalemia (high doses)
Musculoskeletal: Muscle Cramp
Respiratory: Bronchitis, bronchospasm, coughing, tightness of the breath, increased sputum
Other complications: Hypersensitivity reactions
Maintenance:
Keep away from light at temperatures below 30 ° C. Protect frost.
packing:
2 mg syrup per 5 ml: single-numbered package
Saler Company Information
