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The generic name of the drug
Eurofolitropin
Consumption in pregnancy:
X
Pharmacokinetics - Dynamics, Mechanism of Effect
This hormone is produced from the urine of menopausal women. Eurofolitropin contains FSH. FSH and LH together cause the growth and maturity of the ovarian follicles. If human gonadotrophin (hCG), which has the same effect as LH, is prescribed, it is recommended to use Eurofolitropin. The state of the lipid is similar to the natural secretion of LH in the body and ovulation is stimulated.
Consumption by indication
Treatment of female infertility (along with human HCG gonadotropin to stimulate ovulation and induction of pregnancy in patients with polycystic ovary syndrome, in which the ratio of LH / FSH increased or those who did not respond favorably to treatment or clomiphene citrate ):
First, for 7 days or more, 75 units of the IM drug are injected daily. Then, one day after receiving the last dose, 10,000 to 5,000 hCG units are prescribed. If necessary, the dosage may be increased to 150 units once a day for 7 days or more.
Methods of fertilizing women such as IVF or GIFT
150 units are injected once a day in IM. Drug administration begins on the second or third day of the menstrual cycle (the beginning of the follicular phase) and continues until the follicular stage is completed. One day after the last dose of this drug, 10,000 to 5,000 hCG units are prescribed.
Note: Eurofolitropin dosage is determined by the physician's opinion as well as the patient's response to treatment. If the ovaries are abnormally large, the level of estradiol is too high at the last day of follyropin treatment, the administration of hCG in the cycle should not be performed. To be
Contraindications and precautions
The use of eurofolitropin for women with high blood FSH levels indicates primary ovarian failure. In cases where there is uncontrolled impairment of thyroid and extra kidney function, and the presence of intracranial lesions such as the pituitary tumor, for any other cause, infertility, except for ovulation, and in the case of bleeding with an undetermined cause of vagina, who is or large without cause Ovaries, allergy to the drug during pregnancy is prohibited.
Overactive Ovarian Syndrome (OHSS) is associated with rapid fluid accumulation in trait space, thoracic and possibly pericardium, and with early symptoms such as severe pelvic pain, nausea, vomiting, and weight gain. Severe cases of OHSS occur in 0.6% of patients receiving Eurofolitropin. Discontinue use of medication if there is a suspicious indication of OHSS.
HCG should not be used if you have a large ovarian infection before using HCG.
Important drug interactions:
No specific case has been reported.
side effects
The most common is enlargement of the ovary, which is associated with pain and abdominal distension. Big breasts
The most important: cardiovascular arrest, acute respiratory distress syndrome, pulmonary embolism, pulmonary stroke, vascular obstruction, hypersensitivity, and anaphylactic reactions
Other complications: ovarian cyst, ovarian hyperstimulation syndrome, fever, chills, musculoskeletal pain, dyspnea, oliguria, joint pain, nausea, headache, malaise, palpitations, vomiting, rash, dizziness, swelling and irritation Injection site, Tachycardia, Ovarian Norges, Internal bleeding traits, Dry skin, Hair loss, Hives, Ovarian neoplasm, Fatigue and malaise.
Consumption in pregnancy and lactation
Consumption of this drug during pregnancy is associated with death and fetal harm. It is advisable not to use during lactation. Of course, this medicine is not used during lactation.
Poisoning and treatment
Except for excessive ovarian stimulation, another case of acute toxicity has not been reported with this drug.
Medical attention - nursing
1) The contents of one or more ampoules are mixed with half a milliliter of normal saline solution and injected subcutaneously. Discard the remaining solution. 2) Before injection, prepare the prepared solution for color change or sediment particles. 3) The first symptoms of overstimulated ovarian syndrome (OHSS) are severe pain, nausea, vomiting, and weight gain.
Patient education - family
1) Inform the patient about the possibility of multi-treatment. 2) Encourage the patient to treat infertility, close to the day before taking HCG, every day until ovulation. 3) The result of treatment is usually seen 4 to 6 weeks after treatment. 4) Call the doctor immediately if you have any of the following side effects.
Severe heartburn, flushing, swollen hands and feet, nausea, vomiting, diarrhea, weight gain or shortness of breath.
Maintenance
Keep the lipophilic powder at room temperature and away from light. Apply immediately after adding solvent.
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