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Drug category: B-complex, water-soluble vitamin
Pharmacokinetics: After injecting the muscle, absorption will be rapid and almost completely activated by the release and transfer mechanism. This product has renal excretion and can be detected in urine between 50% and 98%. The accumulation of B-vitamins in some organs, such as the spleen, kidney and liver, is higher than other organs.
Mechanism of action: Vitamin B1 (thiamine) plays a key role as a cofactor in the metabolism of carbohydrates and amino acids. This vitamin in the structure of the enzymes transmits two carbon groups to the precursor molecule, for example, pyruvate. Vitamin B6 (pyridoxine / amine) plays a role in the metabolism of amine acids, the production of neurotransmitters, histamine and hemoglobin. This vitamin is present as a cofactor in the structure of enzymes. Vitamin B12 (cobalamin) plays a vital role in the functioning of the nervous system and the nervous system. Making DNA and hemoglobin is one of the other processes that these vitamins play.
Indications:
Deficiency of B vitamins
anemia
Nervous sounds and pains
Chronic nausea and vomiting with a source of vitamin deficiency
Amount and method of administration:
The dose is considered by the doctor. Maximum of one number per day in the form of intramuscular injection
Precautions for use: Vitamin B1 is unstable in alkaline or neutral solutions. Therefore, its administration with carbonates, citrates, barbiturates or copper ions is not recommended. In addition, its stability is poor in venous solutions that include sodium bisulphite (as antioxidant).
Vitamin B12 is inadvertently injected with warfarin sodium for injection. Vitamin B 12 can be used only as an intramuscular injection or oral intake. Avoid intravenous injection.
Consumption during pregnancy: Group B, the use of this drug during pregnancy and lactation should be conducted under the supervision of a specialist physician.
Side effects:
Vitamin B1: Coughing, difficulty in swallowing, urticaria, itching, swelling of the face, lips and eyelid, dyspnea
Vitamin B6: Disorder of body movements, hand and foot anesthesia
Vitamin B 12: Skin rash, dyspnea (at doses above 1000 micrograms)
Packing and storage conditions: 3 ml ampoules in 10-pack, stored at 2 to 8 ° C (in a refrigerator) and away from light.
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