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. What is sinadoxosome and what is it used for?
2. Essential information prior to prescribing
3. How to use the drug
4. Possible side effects
5. Storage conditions
6. Additional information
1. What is sina doxosum and what is it used for?
Sina Doxosum is an anti-tumor medication used to treat metastatic breast cancer, especially in patients with or with cardiac problems, as well as treatment for advanced ovarian cancer.
This drug, along with bortezomib, is used to treat multiple myeloma in patients who have received at least one initial treatment.
It is also used to treat SARS in patients with AIDS. The product contains a drug that can selectively kill cancer cells. Doxorubicin hydrochloride in this product is surrounded by small spherical lipsomes, which helps lead the drug to more cancerous tissue than healthy tissues, which can reduce the side effects of this drug compared to Doxorubicin is standardized.
2. Essential information prior to prescribing
This product should not be prescribed for patients who are susceptible to Doxorubicin Hydrochloride or any of its other components.
The product should be prescribed with caution in the following cases:
If the patient is being treated for heart disease or liver disease.
If the patient is diabetic, it may require a change in diabetes treatment because the product contains sugary compounds.
If the patient is suffering from Kaposi's sarcoma and the spleen is removed.
Taking other medications
You should inform your doctor or pharmacist if:
If you are taking or have recently taken other medications, even if they are over-the-counter.
If you are receiving or have recently received anticancer medicines. Consideration should be given to cures that reduce white blood cell count, as this may result in a further reduction in the number of white blood cells. If the patient has any doubts about what kinds of treatments he or she has received, then they should consult with their physician.
Pregnancy and lactation
Your doctor should consult your doctor or pharmacist before taking the medicine, as doxorubicin hydrochloride in this product may cause fetal defects. If you think you are pregnant, you should discuss this with your doctor. When a patient or spouse is taking this drug and should avoid becoming pregnant even 6 months after it has stopped. Due to the fact that doxorubicin hydrochloride may be harmful to infants in infancy, the patient should stop breast-feeding before starting treatment with this drug.
Driving and doing things thoroughly
If the patient feels tired or drowsy during treatment with this drug, they should refrain from driving and doing things that need to be careful.
3. How to use the drug
The appropriate dosage of sinadoxosome up to 90 mg should be diluted in 250 ml of dextrose 5% and a dose higher than 500 ml of 5% dextrose solution before infusion. The diluted product should be kept at a refrigerated temperature (2 to 8 ° C) and should be used for up to 24 hours.
The performance of liposomal medications in the body may be different from non-liposomal drugs.
Sinadoxosome should not be replaced with other forms of drug containing Doxorubicin Hydrochloride.
Sinadoxosome is given by intravenous infusion, which may take from 30 to 90 minutes depending on the amount of drug used. In the treatment of breast and ovarian cancer, a dose of 50 mg per square meter of body surface area is prescribed every 4 weeks until the disease progresses or the patient is able to tolerate the treatment.
Do not pass through the filter when taking the medicine.
Do not mix the product with other medications.
Do not use diluents other than dextrose solution 5% for infusion.
If you have any deposition in the vial, do not use it.
Do not use bacteriostatic drugs such as benzyl alcohol.
In the treatment of multiple myeloma in patients who have received at least one initial treatment, the drug is given at a dose of 30 mg per square meter of body surface area as an intravenous infusion for one hour, on the fourth day of a three-week regimen Bortezomib is given immediately after infusion of bortezomib and repeated until the patient satisfactorily answers or can tolerate the treatment.
In the treatment of Kaposi's sarcoma, this drug is prescribed at a dose of 20 mg per square meter of body surface area every 2 to 3 weeks for 2-3 months, and thereafter as necessary to maintain the dose.
Taking too much medication
Excessive consumption of the medication can exacerbate side effects such as oral ulcers and reduce white blood cells and platelets in the blood. Treatment for this condition involves the administration of antibiotics, platelet injections, and the use of stimulating factors for the production of white blood cells and symptomatic treatment of oral ulcers.
Ask your doctor or pharmacist if you have more questions.
4. Possible side effects
This drug, like other drugs, can cause side effects, although not everyone can get them.
During the infusion of the drug, the following reactions may occur: reddening of the face, shortness of breath, headache, chills, back pain, chest or throat, sore throat, decreased or increased blood pressure, palpitations, facial puffiness, fever, dizziness Nausea, dyspepsia, itching, rash and depression
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