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Drug Category:
Anti-leishmania (a protozoan parasite causing a disease of the disease) and antifungal
General guidance:
Read carefully the information in this brochure before taking this medicine.
This medicine has been prescribed for your current condition so do not administer it to other people.
If you have more questions, ask your doctor or pharmacist.
• Talk to your doctor if any serious side effects get serious.
Indications:
Amphotericin B is the most effective drug for the treatment of fungal diseases and also protozoan infections such as leishmaniasis, therefore it is used in some cases:
• Treatment of cutaneous cutaneous leishmaniasis caused by different species of Leishmania parasite
Localized recurrent and chronic fungal infections including dermatophytes
The mechanism of the work:
Amphotericin B, by attaching to the cell membranes and forming pores or channels in it, causes changes in the permeability of the cell membrane and intracellular exudates to the outside, and ultimately death and destruction of the cells. The desire for amphotericin B to bind to mushroom membranes and leishmaniasis is approximately 10 times greater than that of mammalian membranes. Therefore, in therapeutic doses, amphotericin B selectively affects mushroom and parasite cells without harm to human cells.
Advantage of Amphotericin B nanoliposomes:
In cutaneous leishmaniasis (Leishmaniasis), the growth site of the Leishmania parasite is inside the infected macrophages in the dermis of the skin. Cinnamomophilus 100 nm nanoliposomes contain amphotericin B, which, after topical application, increases the penetration of the drug into the epidermis and the dermis, and ultimately the infected macrophages of the leishmania parasite, resulting in a high concentration of drug at the site of the parasite. Therefore, the use of liposome increases the efficiency and effectiveness of amphotericin B significantly.
Required Information Before Use:
• Talk to your doctor or pharmacist if you are taking local topicals.
· Avoid contact with the eye.
consumption instruction:
Gently massage the cinnamon gel and apply it twice a day after showering.
• Avoid washing the area of the lesion at least two hours after using the gel.
• Avoid wearing bandages after the use of the drug due to the possibility of skin irritation.
Complete the course of treatment and, if wound healing, do not stop medication discontinuation.
• Avoid using medicine in the eye.
Side effects:
Due to the use of medication, a mild skin reaction may occur, including redness, edema or burning and itching.
Drug Interactions:
Sina-ampoulez gel can be used as part of a topical or systemic combination therapy, avoiding co-administration of this drug with another topical medication on the lesion.
prohibited usage:
Avoid the use of sina-ampoule gel in patients who have shown severe hypersensitivity reactions in previous uses to amphotericin B.
Pregnancy and breastfeeding:
No specific side effects have been reported during pregnancy and lactation.
Storage conditions:
Keep away from children.
Keep at temperatures below 25 ° C and away from heat.
Protect frost.
• After closing the tube, close the door.
· The product can be used up to one month after opening the container door.
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